Description: Segment 1 Muir introduces the lecture. she shows a table listing different qualities of connective tissue and an illustration of a human finger joint. Muir demonstrates the effect of cartilage on bone by using animated plastic models of the human femoral head. Time start: 00:00:00:00 Time end: 00:06:42:00 Length: 00:06:42:00 Segment 2 Muir shows a slide detailing the diagrammatic representation of cartilage, animaged graphic representation of proteoglycan molecules and electron micrographs of cartilage from the human knee. A further graph is used to show how much water is expressed from cartilage. Time start: 00:06:42:00 Time end: 00:12:57:00 Length: 00:06:15:00 Segment 3 Muir talks about and shows diagrams relating to the structure of cartilage proteoglycans molecules. A graph is shown which compares the size of proteoglycans with other proteins, then a graph showing the effect of proteolytic enzymes on proteoglycans. Time start: 00:12:57:00 Time end: 00:19:57:00 Length: 00:07:00:00 Segment 4 An electron micrograph of proteoglycan aggregates is shown, then graphs showing the relative viscosity of proteoglycan aggregates plotted against hyaluronic acid concentration. A further table is used to summarise the way in which proteoglycans interact with a single chain. Time start: 00:19:57:00 Time end: 00:26:26:00 Length: 00:06:29:00 Segment 6 Muir shows an autoradiograph of molecules. She discusses osteoarthritis. Time start: 00:31:27:00 Time end: 00:38:46:00 Length: 00:07:19:00. Segment 7 Muir shows graphs detailing the development of osteoarthritis and a table listing the main features of osteoarthritis. Time start: 00:38:46:00 Time end: 00:43:55:06 Length: 00:05:09:06