Description: Segment 1 Gilliland introduces Roitt. Roitt talks about rheumatoid arthritis, particularly the appearance of inflamed joints in the condition. He shows photomicrographs of these, of plasma cells, of lymphoid follicles, germinal centres and mononuclear cells. Time start: 00:00:00:00 Time end: 00:05:16:00 Length: 00:05:16:00 Segment 2 Roitt draws a diagram of a particle coated with human immunoglobulin gene, then attempts to explain how the autoimmune aspect of arthritis begins. Time start: 00:05:16:00 Time end: 00:10:06:00 Length: 00:04:50:00 Segment 3 Roitt continues to discuss, in detail, how rheumatoid factors arise. Time start: 00:10:06:00 Time end: 00:14:15:12 Length: 00:04:19:12 Segment 4 Roitt talks further, with reference to slides and diagrams, about what it is that triggers an autoimmune reaction in the body chemistry. Time start: 00:14:15:12 Time end: 00:19:40:00 Length: 00:05:24:13 Segment 6 Roitt describes which antigens are responsible for reaction with immunoglobulin G to cause rheumatoid arthritis. He lists some of these. Time start: 00:25:19:12 Time end: 00:30:41:12 Length: 00:05:22:00. Segment 7 Roitt concludes the lecture by saying that, as yet, still little is known definitively about the causes of rheumatoid arthritis. Time start: 00:30:41:12 Time end: 00:35:37:20 Length: 00:04:56:20