Description: Segment 1 Dr Garrow begins by referring to a previous video in the 'Uptodate' series on the cause of obesity and summarises key points made about obesity in that video with the aid of weight/height charts. He says this video is about people who would benefit from weight loss. A chart shows input of energy as food and output of energy as physical activity, and Garrow says that the output must be larger than the input for weight loss to occur. Time start: 00:00:00:00 Time end: 00:05:03:07 Length: 00:05:03:07 Segment 2 A sketch of Daniel Lambert (famous obese man in 18th century) is shown and Garrow shows a mathematical equation relating to his weight. He then discusses a basic plan for weight loss that could be devised by a physician and dietician, then discusses the people who most benefit from weight loss. He shows a photograph of a naked elderly lady and says that weight loss should have occurred years ago and would not affect her now. He shows another photograph of a man in his 30s, who would benefit from weight loss. A photograph of a severely overweight woman in her 30s is shown whose life may be endangered by her weight. A graph showing mortality ratio with weight is shown and Garrow explains the data. Time start: 00:05:03:07 Time end: 00:10:32:01 Length: 00:05:28:19 Segment 3 Garrow continues to discuss the data in the mortality graph. Another chart is shown of data provided by a general practitioner who treated 43 obese patients over 10 years. Garrow discusses the varied results and says that young patients are the people upon whom the most effort should be concentrated. Another diagram of weight loss in a group of patients on supervised diets is shown. Over time, the results vary. Time start: 00:10:32:01 Time end: 00:14:36:20 Length: 00:04:04:19 Segment 4 Garrow talks over an earlier flow chart, discussing metabolic rates and thermogenic drugs. He does not recommend these drugs and says that a slow weight loss should be accepted instead. He also talks about the importance of encouraging patients to stay on their diet and why they might not do this. He suggests that anorectic drugs may be helpful for some people for a short time, as may psychotherapy. Garrow then discusses surgical treatments, including wiring the teeth shut and gastric bypasses. A photograph of a gastrointestinal tract is shown, and Garrow describes the jejuno ileal bypass in detail. Time start: 00:14:36:20 Time end: 00:21:33:20 Length: 00:06:57:00